Vol. 33 – Genetics and orthodontics and dentofacial orthopedics

Vol. 33 – Genetics and orthodontics and dentofacial orthopedics

Summary 

INTRODUCTION

Why is genetics interesting for clinical orthodontics?

Individual alterations of form and structure

THE HISTORY OF GENETICS: FROM MENDEL TO TODAY

The relationship between genetype and phenotype

Quantitative genetics

The variability of the phenotype conditioned by the environment

Does Genetics in Orthodontics mark the limit of orthodontic success?

GENETIC DETERMINANTS OF CRANIOFACIAL GROWTH DURING EMBRYONIC LIFE

What are homeotic genes?

How do homeotic genes function?

Why is it important to know them?

GENETIC DETERMINANTS OF CRANIOFACIAL GROWTH IN POSTNATAL LIFE

What happens as a result of mandibular advancement at the level of the condylar cartilage?

How does bone replace the cartilage in the condyle?

What triggers the onset of ossification of the condylar cartilage?

Is there a relationship between arch form and the shape of the mandible?

Mandibular growth: form and rotation

MOLECULAR BIOLOGY AND DENTAL MOVEMENT

Theories of tooth movement

Signal molecules and metabolites in orthodontic tooth movement

Mechanotransduction

Osteogenesis in the area of tension

Bone resorption in the area of pressure

Tooth movement and corticotomy

Dental movement and drug interactions

Bibliography